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Understanding the role of sleep and its disturbances in Autism spectrum disorder

Ramanujam Karthikeyan1, Daniel P Cardinali2, Venkat Shakunthala3

  • 1Department of Animal Behavior & Physiology, School of Biological Sciences, Madurai Kamaraj University, Madurai, Tamil Nadu, India.

The International Journal of Neuroscience
|January 7, 2020
PubMed

Insights

Sleep difficulties are common in children with autism spectrum disorder (ASD) and are linked to increased symptom severity. Addressing these sleep issues is crucial for improving overall well-being in ASD individuals.

Area of Science:

  • Neuroscience
  • Developmental Pediatrics
  • Sleep Medicine

Background:

  • Autism spectrum disorder (ASD) is frequently associated with sleep difficulties.
  • These sleep problems significantly contribute to the overall symptomatology in children with ASD.

Purpose of the Study:

  • To comprehensively review and discuss sleep disorders in individuals with ASD.
  • To highlight the growing clinical and familial attention towards sleep disturbances in ASD.

Main Methods:

  • A narrative overview based on extensive literature searches of standard research databases.
  • Inclusion of articles from bibliographies of retrieved papers and author's curated collection.
  • Qualitative comparison and summarization of selected manuscripts from an author's perspective.

Main Results:

  • Sleep plays a vital role in brain and neural development, particularly in children.
  • The severity of sleep problems in ASD individuals correlates with increased ASD symptom occurrence.
  • Treatment of sleep problems is suggested as significant for managing ASD.

Conclusions:

  • This review offers enhanced understanding of sleep problems in ASD, covering pathophysiology, mechanisms, and management.
  • Implications for clinical practice and future research agendas are discussed.
  • Provides a broader perspective on the connection between sleep and ASD.
Abstract

Keywords:
ASDAutism spectrum disorderSleepSleep problemsmelatonintreatment of ASD

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