Related Experiment Video
Updated: Dec 31, 2025

Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers
Published on: July 17, 2012
Technical background of a novel detector-based approach to dual-energy computed tomography
Nils Große Hokamp1, David Maintz1, Nadav Shapira2
1Department of Diagnostic and Interventional Radiology, University Hospital Cologne, Institute for Diagnostic and Interventional Radiology, Cologne, Germany.
Abstract:
Dual-energy information in computed tomography can be obtained through different technical approaches. Most available scanner designs acquire examination with two different X-ray spectra. Recently, the first detector-based approach became clinically available. Upfront, physical principles of dual-energy CT are reviewed, including the interaction of photons with matter in terms of the Photoelectric effect and Compton scattering. In addition, available concepts to dual energy computed tomography are described. Afterwards, the spectral detector CT system is described in detail. The design of the of the stacked detector design and its inherent technical advantages and disadvantages are discussed. Further, the principles of image reconstruction, their possibilities and limitations are referred. The increase in reconstructions and data pose some challenges to both, clinical and technological workflow which are hereafter addressed. Finally, the detector-based approach is discussed in light of other, emission-based DECT approaches.
Related Concept Videos
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
X-ray Imaging
Imaging Studies III: Computed Tomography
Imaging Studies for Cardiovascular System V: CT
Positron Emission Tomography
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
Imaging Studies II: Positron Emission Tomography and Scintigraphy
Fundamental Principles of PET

