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Related Concept Videos

Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

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The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
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Asthma-IV: Nursing Management01:30

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The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
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Asthma: Pathogenesis and Management01:20

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
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Asthma-I: Introduction01:29

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Asthma-II: Pathophysiology and Classification01:26

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Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
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Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

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Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
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Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
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Optimal Asthma Control: Time for a New Target.

Richard Beasley1,2,3, Irene Braithwaite1, Alex Semprini1

  • 1Medical Research Institute of New Zealand, Wellington, New Zealand.

American Journal of Respiratory and Critical Care Medicine
|January 7, 2020
PubMed
Summary
This summary is machine-generated.

Achieving optimal asthma control in adults may require higher inhaled corticosteroid doses and addressing comorbidities. Further research is needed to define ideal treatment targets for better asthma management.

Keywords:
asthmacontrolguidelinespharmacological treatment

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Area of Science:

  • Pulmonology
  • Pharmacology
  • Clinical Medicine

Background:

  • Current stepwise pharmacological treatment for adult asthma aims for symptom control and reduced exacerbations.
  • Achieving well-controlled asthma is challenging, with approximately 70% of patients reaching this goal.
  • Asthma management is complicated by overlapping disorders, comorbidities, and environmental factors impacting control.

Purpose of the Study:

  • To review the effectiveness of current asthma treatment strategies in adults.
  • To explore factors contributing to suboptimal asthma control and potential new treatment targets.
  • To investigate the relationship between symptom control, quality of life, and risk of exacerbations.

Main Methods:

  • Review of existing literature on adult asthma pharmacological treatment.
  • Analysis of factors influencing asthma control, including comorbidities and environmental influences.
  • Discussion of current treatment targets and their limitations in achieving complete risk elimination.

Main Results:

  • Optimal asthma control may necessitate inhaled corticosteroid/long-acting β2 agonist therapy escalation.
  • Dose escalation should consider systemic side effects comparable to low-dose oral prednisone.
  • Patient perception of control may differ from guideline assessments, potentially due to minimal impairment despite partial control.

Conclusions:

  • Current asthma treatment may not achieve optimal control or eliminate exacerbation risk in all patients.
  • Addressing comorbidities and environmental factors is crucial for improving asthma outcomes.
  • Further research is needed to define optimal asthma control levels and explore novel treatment targets like type-2 airway inflammation.