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Related Concept Videos

Other Disorders of Digestive System01:30

Other Disorders of Digestive System

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The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
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Inflammatory Bowel Disease II: Crohn's Disease01:30

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
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Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

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Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
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Gastritis-II: Pathophysiology01:17

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Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
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Chronic Bowel Disorders: Introduction01:17

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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
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Inflammatory Bowel Disease I: Ulcerative Colitis01:27

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Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
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Celiac Disease.

Joshua Elliott Rubin1, Sheila E Crowe1

  • 1University of California, San Diego School of Medicine, La Jolla, California (J.E.R., S.E.C.).

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|January 7, 2020
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Summary
This summary is machine-generated.

Gluten-related disorders like celiac disease and nonceliac gluten sensitivity (NCGS) are rising globally. Management involves strict gluten-free diets and specialist care for celiac disease patients.

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Area of Science:

  • Gastroenterology and Immunology
  • Nutritional Science

Background:

  • Gluten-related disorders, including celiac disease, wheat allergy, and nonceliac gluten sensitivity (NCGS), are increasingly prevalent worldwide.
  • Celiac disease involves an immune response to gluten in genetically susceptible individuals.
  • Nonceliac gluten sensitivity (NCGS) is diagnosed after excluding other conditions.

Purpose of the Study:

  • To provide a comprehensive overview of gluten- and wheat-related disorders.
  • To highlight the increasing global incidence of these conditions.
  • To outline current understanding and management approaches.

Main Methods:

  • Literature review of gluten-related disorders.
  • Synthesis of information on celiac disease, wheat allergy, and NCGS.
  • Summary of diagnostic criteria and management strategies.

Main Results:

  • Gluten-related disorders are on the rise globally.
  • Celiac disease is an immune reaction to gluten in susceptible individuals.
  • NCGS is a diagnosis of exclusion.

Conclusions:

  • Patients with celiac disease require lifelong adherence to a strict gluten-free diet.
  • Referral to specialized dietitians and gastroenterologists is crucial for celiac disease management.
  • Understanding these disorders is key for effective patient care and public health.