Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pain Assessment and Management in Pediatric Trauma Patients Transported to an Emergency Department: A Retrospective Cohort Study.

Children (Basel, Switzerland)·2026
Same author

Co-Delivery of 8-Hydroxyquinoline Glycoconjugates and Doxorubicin by Supramolecular Hydrogel Based on α-Cyclodextrin and pH-Responsive Micelles for Enhanced Tumor Treatment.

Pharmaceutics·2022
Same author

Glycoconjugation of Quinoline Derivatives Using the C-6 Position in Sugars as a Strategy for Improving the Selectivity and Cytotoxicity of Functionalized Compounds.

Molecules (Basel, Switzerland)·2022
Same author

Shell-Sheddable Micelles Based on Poly(ethylene glycol)-hydrazone-poly[R,S]-3-hydroxybutyrate Copolymer Loaded with 8-Hydroxyquinoline Glycoconjugates as a Dual Tumor-Targeting Drug Delivery System.

Pharmaceutics·2022
Same author

Synthesis and Preliminary Evaluation of the Cytotoxicity of Potential Metabolites of Quinoline Glycoconjugates.

Molecules (Basel, Switzerland)·2022
Same author

From Anionic Ring-Opening Polymerization of β-Butyrolactone to Biodegradable Poly(hydroxyalkanoate)s: Our Contributions in This Field.

Polymers·2021

Related Experiment Video

Updated: Dec 31, 2025

The Synthesis of RGD-functionalized Hydrogels as a Tool for Therapeutic Applications
09:30

The Synthesis of RGD-functionalized Hydrogels as a Tool for Therapeutic Applications

Published on: October 7, 2016

11.8K

α-Cyclodextrin-Based Polypseudorotaxane Hydrogels.

Adrian Domiński1, Tomasz Konieczny1, Piotr Kurcok1

  • 1Centre of Polymer and Carbon Materials, Polish Academy of Sciences, 34, M. Curie-Sklodowskiej St., 41-819 Zabrze, Poland.

Materials (Basel, Switzerland)
|January 8, 2020
PubMed
Summary
This summary is machine-generated.

Discover supramolecular hydrogels using alpha-cyclodextrin and polymers. These smart materials leverage dynamic noncovalent bonds for flexible, stimuli-responsive applications.

Keywords:
polypseudorotaxaneself-assemblysupramolecular hydrogelsα-cyclodextrin

More Related Videos

Transport Properties of Ibuprofen Encapsulated in Cyclodextrin Nanosponge Hydrogels: A Proton HR-MAS NMR Spectroscopy Study
10:10

Transport Properties of Ibuprofen Encapsulated in Cyclodextrin Nanosponge Hydrogels: A Proton HR-MAS NMR Spectroscopy Study

Published on: August 15, 2016

10.6K
Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning
12:07

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

Published on: April 16, 2018

13.9K

Related Experiment Videos

Last Updated: Dec 31, 2025

The Synthesis of RGD-functionalized Hydrogels as a Tool for Therapeutic Applications
09:30

The Synthesis of RGD-functionalized Hydrogels as a Tool for Therapeutic Applications

Published on: October 7, 2016

11.8K
Transport Properties of Ibuprofen Encapsulated in Cyclodextrin Nanosponge Hydrogels: A Proton HR-MAS NMR Spectroscopy Study
10:10

Transport Properties of Ibuprofen Encapsulated in Cyclodextrin Nanosponge Hydrogels: A Proton HR-MAS NMR Spectroscopy Study

Published on: August 15, 2016

10.6K
Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning
12:07

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

Published on: April 16, 2018

13.9K

Area of Science:

  • Materials Science
  • Polymer Chemistry
  • Supramolecular Chemistry

Background:

  • Supramolecular hydrogels utilize dynamic noncovalent bonds, like host-guest interactions, for crosslinking.
  • Alpha-cyclodextrin and (co)polymers form inclusion complexes, creating promising smart hydrogel materials.
  • These hydrogels offer flexibility and stimuli-responsiveness, contrasting with traditional covalent crosslinking.

Purpose of the Study:

  • To review the design and synthesis of alpha-cyclodextrin-based supramolecular polypseudorotaxane hydrogels.
  • To highlight the chemistry and methods involved in creating these advanced materials.
  • To explore the potential applications of these novel hydrogels.

Main Methods:

  • Formation of polypseudorotaxanes through host-guest complexation between alpha-cyclodextrin (host) and (co)polymer chains (guest).
  • Utilizing dynamic noncovalent interactions, including host-guest and hydrogen bonds, for supramolecular crosslinking.
  • Incorporating various polymer architectures or polymeric nanoparticles as guests within the hydrogel network.

Main Results:

  • Alpha-cyclodextrin-based polypseudorotaxane hydrogels exhibit excellent biocompatibility and thixotropic behavior.
  • These hydrogels demonstrate reversible and stimuli-responsive properties, enabling tunable material characteristics.
  • The self-assembly process allows for the creation of functional materials with diverse architectures.

Conclusions:

  • Alpha-cyclodextrin-based supramolecular polypseudorotaxane hydrogels are versatile platforms for advanced material development.
  • Their unique properties, including dynamic crosslinking and responsiveness, open avenues for innovative applications.
  • Continued research in their chemistry and design promises significant advancements in functional materials engineering.