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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
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Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
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Lesson: Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
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Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
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A Translational Approach to Cancer Research, Education and Training.

Heather J Ezelle1, Theresa Geiman2, Lauren A Schnaper3

  • 1University of Maryland Greenebaum Comprehensive Cancer Center, 108 N. Greene St., Baltimore, MD, 21201, USA.

Journal of Cancer Education : the Official Journal of the American Association for Cancer Education
|January 8, 2020
PubMed
Summary
This summary is machine-generated.

The Nathan Schnaper Intern Program (NSIP) enhanced its translational cancer research training. New modules improved intern satisfaction, learning, and career trajectories in oncology.

Keywords:
Cancer educationLaboratory researchSummer internshipTranslationalUndergraduate

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Area of Science:

  • Biomedical research
  • Health sciences
  • Cancer research and oncology

Background:

  • Increasing demand for biomedical researchers and health science professionals, especially in oncology.
  • Technological advances drive rapid discoveries and applications in cancer diagnostics and therapeutics.
  • Internships are crucial for educating students about cancer research careers and inspiring pursuit of these paths.

Purpose of the Study:

  • Evaluate the impact of three new modules in the Nathan Schnaper Intern Program in Translational Cancer Research (NSIP).
  • Assess the effectiveness of research, education, and clinical components implemented with National Cancer Institute funding.
  • Identify optimal approaches and key outcome measures for intern satisfaction, learning, and career trajectory.

Main Methods:

  • Implementation of three new modules within the NSIP.
  • Assessment of intern satisfaction, learning outcomes, and near-term career trajectory.
  • Analysis of program data collected over the first two years of National Cancer Institute Cancer Research Education Grants Program funding.

Main Results:

  • The study evaluates the impact of newly implemented modules on intern experience.
  • Data analysis focuses on intern satisfaction, knowledge acquisition, and career path development.
  • Outcomes are assessed to determine the most effective program components and measures.

Conclusions:

  • The NSIP's new modules aim to enhance undergraduate training in translational cancer research.
  • Program evaluation seeks to refine approaches for cultivating future cancer physician-scientists.
  • Findings will inform best practices for cancer research education and workforce development.