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Published on: November 30, 2022
Multiple Electrophilic C-H Borylation of Arenes Using Boron Triiodide
Susumu Oda1, Kenta Ueura1, Bungo Kawakami1
1Department of Chemistry, School of Science and Technology , Kwansei Gakuin University , 2-1 Gakuen , Sanda , Hyogo 669-1337 , Japan.
Abstract:
Electrophilic C-H borylation of arenes using boron triiodide has been developed. This reaction proceeded smoothly in the absence of additives, and the diiodoboryl group was installed at the most sterically accessible carbon, where the HOMO is localized to a certain extent. Moreover, regioselective multiple borylation of polycyclic aromatic compounds was achieved by using excess boron triiodide. The borylated intermediates were transformed into a variety of arylboron compounds such as arylboronates, boronic acids, and trifluoroborates.
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