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Vitiligo - New Treatment Approach
Veronika A Konstantinova1, Olga Yu Olisova2, Victor V Gladko3
1Dermatology and Cosmetology Department Dao Clinic, Leninskiy Prospekt, Moscow 119119, Russia.
Clinical, Cosmetic and Investigational Dermatology
|January 8, 2020
Summary
Intradermal injections of NCTF 135, a vitamin and mineral complex, effectively treated vitiligo, leading to skin repigmentation in all patients. This novel mesotherapy approach showed significant results with no adverse effects.
Area of Science:
- Dermatology
- Cosmetic Science
- Regenerative Medicine
Background:
- Vitiligo is a common hypopigmentation disorder with limited treatment options.
- Current therapies include UV, topical corticosteroids, and calcineurin inhibitors.
- Oral vitamins and UV light have shown some success in repigmentation.
Purpose of the Study:
- To evaluate a novel treatment for vitiligo using intradermal injections.
- To assess the efficacy and safety of NCTF 135 in repigmenting vitiligo patches.
Main Methods:
- A pilot study involving seven patients with generalized progressive vitiligo.
- Intradermal injections of NCTF 135 (biorevitalizant) administered weekly for five weeks.
- Assessment of skin repigmentation at two and five weeks post-treatment.
Main Results:
- 100% of patients achieved partial or complete skin repigmentation.
- No significant side effects or vitiligo exacerbation were observed.
- Positive outcomes were sustained for up to 12 months in some patients.
Conclusions:
- Intradermal NCTF 135 mesotherapy is a well-tolerated and effective treatment for vitiligo.
- This approach offers a promising new option, especially for patients resistant to conventional therapies.
- The antioxidant properties of NCTF 135 likely contribute to its efficacy in skin repigmentation.
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