Related Experiment Video

Updated: Dec 31, 2025

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
05:16

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure

Published on: June 10, 2025

478

Blood pressure and heart failure

Gyu Chul Oh1, Hyun-Jai Cho1

  • 1Cardiovascular Center & Department of Internal Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, South Korea.

Clinical Hypertension
|January 8, 2020
PubMed

Insights

Hypertension management is crucial for preventing heart failure. While current guidelines suggest a blood pressure target near 130/80 mmHg for heart failure patients, further research is needed to confirm optimal targets.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Heart Failure Management

Background:

  • Hypertension is a major global risk factor for cardiovascular diseases, stroke, and mortality.
  • It is often underdiagnosed and undertreated, contributing to significant public health burden.
  • Sustained high blood pressure can lead to left ventricular hypertrophy and diastolic dysfunction, increasing myocardial rigidity.

Purpose of the Study:

  • To review the importance of blood pressure control in preventing heart failure progression.
  • To discuss the complexities of blood pressure management in patients with established heart failure, particularly those with preserved ejection fractions.
  • To highlight the need for evidence-based optimal blood pressure targets in heart failure.

Main Methods:

  • Review of existing literature and current clinical guidelines on hypertension and heart failure.
  • Analysis of the potential risks associated with aggressive blood pressure lowering in heart failure.
  • Examination of the 'reverse J-curve' phenomenon in relation to blood pressure and outcomes in heart failure.

Main Results:

  • Adequate blood pressure control is essential to prevent the progression of hypertension to overt heart failure.
  • Blood pressure management is also vital in established heart failure, especially with preserved ejection fractions.
  • A potential 'reverse J-curve' association suggests that overly aggressive blood pressure reduction may lead to adverse outcomes in heart failure patients.

Conclusions:

  • Current guidelines suggest a blood pressure target near 130/80 mmHg for heart failure patients.
  • Robust evidence regarding the optimal blood pressure target in heart failure remains limited.
  • Prospective studies are necessary to definitively determine the ideal blood pressure targets for patients with heart failure.
Abstract

Keywords:
Diastolic dysfunctionHeart failureHypertensionJ-curveLeft ventricular hypertrophy

More Related Videos

A Model of Reverse Vascular Remodeling in Pulmonary Hypertension Due to Left Heart Disease by Aortic Debanding in Rats07:41

A Model of Reverse Vascular Remodeling in Pulmonary Hypertension Due to Left Heart Disease by Aortic Debanding in Rats

Published on: March 1, 2022

3.3K
Author Spotlight: Investigating HR-Dependent Cardiac Function in Mouse Models Through a Novel Atrial-Pacing Approach07:49

Author Spotlight: Investigating HR-Dependent Cardiac Function in Mouse Models Through a Novel Atrial-Pacing Approach

Published on: July 21, 2023

1.8K

Related Concept Videos

Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
2.6K
Heart Failure I: Introduction01:27

Heart Failure I: Introduction

Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
618
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
612
Heart Failure VII: Nursing Interventions01:30

Heart Failure VII: Nursing Interventions

The first step in nursing management of a patient with heart failure involves thoroughly assessing the patient's medical history.Subjective Data: Obtain the patient's medical history of coronary artery disease, hypertension, myocardial infarction, and symptoms like dyspnea, orthopnea, and paroxysmal nocturnal dyspnea.Objective Data: Conduct a physical examination to identify findings such as jugular vein distention, pulmonary crackles, tachycardia, murmurs, peripheral edema, and vital signs,...
366
Heart Failure IV: Classification and Diagnostic Evaluation01:30

Heart Failure IV: Classification and Diagnostic Evaluation

Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
252
Measurement of Blood Pressure01:17

Measurement of Blood Pressure

Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a...
2.5K