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Ion Exchange01:17

Ion Exchange

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Ion exchange chromatography separates charged molecules from a solution by reversibly exchanging them with mobile, or 'active', ions associated with the oppositely charged stationary phase. This method can be used to separate ions, soften and deionize water, and purify solutions. The polymers comprising the ion-exchange column are high-molecular-weight and chemically stable polymers, crosslinked to be porous and essentially insoluble. They are also functionalized with either acidic or...
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Extraction: Advanced Methods00:56

Extraction: Advanced Methods

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Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
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Ion-Exchange Chromatography01:09

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Ion-exchange chromatography, or IEC, is a technique for separating ions based on their affinity for the stationary phase. The stationary phase is a cross-linked polymer resin with covalently attached ionic functional groups. The functional groups can be either positively charged (cation exchangers) or negatively charged (anion exchangers). A cation exchanger consists of a polymeric anion and active cations, while an anion exchanger is a polymeric cation with active anions. The choice of...
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Extraction: Effects of pH00:53

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Consider a neutral form of an amine, B, with a partition coefficient, K, in a liquid mixture containing organic and aqueous phases. The pH of the aqueous phase affects the charge on acidic and basic solutes, and the charged form is usually more soluble in the aqueous phase. Suppose the conjugate acid form of the amine is soluble only in the aqueous phase while the base form is soluble in both phases. Then the distribution coefficient, D, can be given as the ratio of amine concentration in the...
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High-Performance Liquid Chromatography: Introduction01:11

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High-performance liquid chromatography(HPLC), formerly referred to as High-pressure liquid chromatography, is a powerful technique used to separate, identify, and quantify components in complex mixtures. The term "high pressure" refers to using high pressure to push the liquid mobile phase through the tightly packed columns.
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Aqueous Biphasic Systems Containing Customizable Poly(Ionic Liquid)s for Highly Efficient Extractions.

Yuqi Ke1, Jingzhu Zhang1, Yuanbang Xie1

  • 1Key Laboratory of Biomass Chemical Engineering of Ministry of Education, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, 310027, P.R. China.

Chemsuschem
|January 8, 2020
PubMed
Summary
This summary is machine-generated.

Novel poly(ionic liquid)s create advanced aqueous biphasic systems (ABSs) for efficient bioactive compound extraction. These tailored systems offer superior phase separation and high recovery yields, outperforming traditional methods.

Keywords:
biphasic systemsextractionsionic liquidspolymerizationseparation

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Area of Science:

  • Polymer Chemistry
  • Separation Science
  • Green Chemistry

Background:

  • Aqueous biphasic systems (ABSs) offer sustainable alternatives for liquid-liquid extraction.
  • Developing high-performance ABSs with effective phase separation and extraction capabilities remains a challenge.
  • Ionic liquids (ILs) are explored for ABSs, but polymer-based systems offer enhanced tunability.

Purpose of the Study:

  • To prepare novel poly(ionic liquid)s (PILs) for customized aqueous biphasic systems (ABSs).
  • To evaluate the phase separation and extraction performance of PIL-based ABSs for bioactive compounds.
  • To demonstrate the tunability of PIL-based ABSs by altering molecular weight and counteranion.

Main Methods:

  • Synthesis of tailor-made PILs via reversible addition fragmentation chain-transfer polymerization.
  • Construction of PIL-based aqueous biphasic systems (ABSs).
  • Extraction and quantification of six model bioactive compounds (e.g., tryptophan, phenylalanine, caffeine).

Main Results:

  • PIL-based ABSs exhibited excellent phase separation, surpassing IL monomers and conventional polymers.
  • Unprecedentedly high partition coefficients and extraction yields were achieved for target bioactive compounds.
  • System performance was tunable by modifying PIL molecular weight and counteranion type.

Conclusions:

  • Tailor-made PIL-based ABSs represent a promising platform for efficient bioactive compound extraction and purification.
  • The design of PILs with controlled structures enables optimization of ABS performance.
  • This study provides insights for developing advanced separation systems for diverse applications.