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Updated: Dec 31, 2025

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Clinical and radiological features of mesenteric panniculitis: a critical overview
Giuseppe Buragina1, Alberto Magenta Biasina, Gianpaolo Carrafiello
1Università degli studi di milano. giuseppe.buragina@unimi.it.
Abstract:
The mesenteric panniculitis is a rare form of inflammation that mainly involves the mesenteric adipose tissue. The etiology remains unknown and the disease has been associated with various conditions such as cancer, abdominal trauma, previous surgery, autoimmune diseases and obesity. Mesenteric panniculitis can be divided into two main groups: the mesenteric panniculitis with only the inflammation and degeneration of the mesenteric fat, and the retractile panniculitis, mainly fibrotic, with retraction of the surrounding structures. From a radiological point of view, there are two main signs: the fat ring sign, which is the presence of normal fat around vessels and lymph nodes, and the pseudocapsula around the lesion. In this paper, we present the imaging and clinical features of mesenteric panniculits with particular reference to the differential diagnosis and the possible etiological associations. (www.actabiomedica.it).
Insights
Mesenteric panniculitis is a rare inflammation of the mesenteric fat. This study reviews its imaging and clinical features, differential diagnoses, and associated conditions.
Area of Science:
- Gastroenterology
- Radiology
- Pathology
Background:
- Mesenteric panniculitis is a rare inflammatory condition affecting mesenteric adipose tissue.
- Its etiology is unknown, but it's linked to cancer, trauma, surgery, autoimmune diseases, and obesity.
- It presents as inflammatory or fibrotic (retractile) forms.
Purpose of the Study:
- To present the imaging and clinical features of mesenteric panniculitis.
- To highlight key radiological signs like the fat ring sign and pseudocapsula.
- To discuss differential diagnoses and potential etiological associations.
Main Methods:
- Review of imaging findings (radiology).
- Analysis of clinical presentations.
- Correlation with pathological findings and etiological factors.
Main Results:
- Identified characteristic radiological signs: fat ring sign and pseudocapsula.
- Detailed the clinical manifestations and varied associations of the condition.
- Distinguished between inflammatory and fibrotic subtypes.
Conclusions:
- Mesenteric panniculitis requires careful radiological and clinical evaluation for accurate diagnosis.
- Understanding its associations is crucial for patient management.
- Further research into etiology may improve treatment strategies.
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