Related Experiment Video
Updated: Dec 31, 2025

Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension
Published on: June 6, 2025
Uncontrolled Blood Pressure in Hypertensive Patients with High Medication Adherence: A Korean Nationwide
Jiwon Kwon1, Chi-Yeon Lim2, Minkyeong Kim1
1Department of Family Medicine, Hongik Hospital, Seoul, Korea.
Insights
Uncontrolled systolic and diastolic blood pressure (BP) in Korean adults with high medication adherence is linked to various factors. Older age, female sex, and diabetes are associated with uncontrolled systolic BP, while heavy alcohol consumption impacts both.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- Uncontrolled blood pressure (BP) remains prevalent despite antihypertensive medication.
- High medication adherence is crucial for effective hypertension management.
- Understanding factors associated with uncontrolled BP is vital for targeted interventions.
Purpose of the Study:
- To investigate factors associated with uncontrolled systolic blood pressure (SBP) and diastolic blood pressure (DBP) separately.
- To analyze these factors in Korean hypertensive patients with high medication adherence.
- To identify specific predictors for SBP and DBP control in this population.
Main Methods:
- A population-based cross-sectional study using data from the Korea National Health and Nutrition Examination Survey (2013-2015).
- Inclusion of 3,236 hypertensive patients with high medication adherence (daily antihypertensive use).
- Logistic regression analysis to determine associations between uncontrolled SBP (≥140 mmHg) or DBP (≥90 mmHg) and various demographic, lifestyle, and clinical factors.
Main Results:
- Prevalence of uncontrolled SBP was 23.3% and uncontrolled DBP was 9.0%.
- Uncontrolled SBP associated with older age, female sex, blue-collar/no work, spouse presence, short sleep, heavy alcohol use, longer hypertension duration, diabetes, stroke, and missed medication; negatively associated with high stress.
- Uncontrolled DBP associated with heavy alcohol use; negatively associated with older age, blue-collar/no work, and diabetes.
Conclusions:
- Various factors are associated with uncontrolled SBP and DBP in Korean adults with treated hypertension, even with high medication adherence.
- Distinct factors influence uncontrolled systolic and diastolic blood pressure.
- Separate analysis of SBP and DBP is valuable for understanding hypertension control factors.
Background:
Uncontrolled blood pressure (BP) is relatively common despite treatment with antihypertensive medication. This study aimed to investigate factors associated with uncontrolled systolic BP (SBP) and diastolic BP (DBP) separately in hypertensive patients with high medication adherence in Korea.
Methods:
This population-based cross-sectional study included 3,236 participants in the Korea National Health and Nutrition Examination Survey from 2013 to 2015. Hypertensive patients with high medication adherence were defined when they stated that they were taking antihypertensive medication daily. "Uncontrolled SBP and DBP" were defined as SBP ≥140 mm Hg and DBP ≥90 mm Hg, respectively. Data were analyzed using logistic regression to determine the association between uncontrolled SBP or DBP and various factors.
Results:
The prevalence of uncontrolled SBP and uncontrolled DBP was 23.3%, and 9.0%, respectively. In multivariate analysis, uncontrolled SBP was positively associated with older age, female sex, blue-collar occupation or no work (vs. white-collar), presence of a spouse, short sleep duration, frequent heavy alcohol drinking, longer hypertension duration, diabetes, stroke, and missing antihypertensive medication on the examination day, but negatively associated with high stress. Uncontrolled DBP was positively associated with frequent heavy alcohol drinking, but negatively associated with older age, blue-collar occupation or no work (vs. white-collar), and diabetes.
Conclusion:
After excluding low medication adherence, we identified various factors associated with uncontrolled SBP or DBP in Korean adults with treated hypertension. There were differences between factors associated with uncontrolled SBP or DBP. Separate analysis of SBP and DBP may help understand the factors involved in BP control.
Related Concept Videos
Hypertension IV: Drug Therapy and Lifestyle Modifications
Hypertension III: Clinical Manifestations and Diagnostic Studies
Hypertension and Regulation of Blood Pressure
Errors occurring during blood pressure monitoring
Several factors...
Hypertension I: Introduction
Hypertension V: Nursing Management

