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Related Experiment Video

Updated: Dec 31, 2025

Customizing a Cryolite Glass Prosthetic Eye

Customizing a Cryolite Glass Prosthetic Eye

Published on: October 31, 2019

Eye Socket Regeneration and Reconstruction.

M Borrelli¹, G Geerling¹, K Spaniol¹

¹Department of Ophthalmology, University Hospital Duesseldorf, Duesseldorf, Germany.

Current Eye Research

|January 9, 2020

Summary

This summary is machine-generated.

Reconstructing the anophthalmic socket often requires tissue substitution. Current methods use amniotic membrane or oral mucosa, with ongoing research into tissue-engineered grafts for future ocular socket restoration.

Keywords:

Orbital soft tissue conjunctiva orbital implants reconstruction regeneration socket transplantation

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Three-Dimensional Reconstruction of Orbital Fractures

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Three-Dimensional Reconstruction of Orbital Fractures

Three-Dimensional Reconstruction of Orbital Fractures

Published on: May 16, 2025

Area of Science:

Ophthalmology
Biomaterials Science
Regenerative Medicine

Background:

Anophthalmic socket reconstruction is crucial for cosmesis after eye removal.
Tissue loss due to trauma, tumors, or disease complicates prosthesis fitting.
Effective tissue substitution strategies are needed for challenging cases.

Purpose of the Study:

To review literature on indications, surgical techniques, and materials for ocular socket restoration.
To identify current standards and emerging alternatives for anophthalmic socket reconstruction.

Main Methods:

Literature search of electronic databases (PubMed, MEDLINE).
Analysis of studies on surgical techniques and materials for ocular socket reconstruction.

Main Results:

Amniotic membrane and oral mucosa are primary reconstructive materials.
Synthetic scaffolds and tissue-engineered grafts show preclinical promise but require further clinical validation.
Porous/nonporous spheres are effective for orbital volume replacement; dermofat grafts suit significant tissue loss.

Conclusions:

Established techniques involve autologous/allogeneic tissues.
Tissue engineering using scaffolds and stem cells offers future alternatives for ocular socket reconstruction.