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Updated: Dec 31, 2025

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus KSHV
Published on: September 14, 2010
HHV-8-negative multicentric Castleman disease presenting as a crescentic immune complexes membranoproliferative
Maria Brito Nunes1, Samuel Rotman2, Francois-Regis Duss3
1Internal Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland lucilia.b.nunes@gmail.com.
Abstract:
Multicentric Castleman disease is a rare polyclonal lymphoproliferative disorder mainly associated with two renal manifestations: thrombotic microangiopathy and amyloidosis. Nevertheless, we report here a case of human herpes virus-8 negative multicentric Castleman disease with membranous proliferative glomerulonephritis and extracapillary proliferation. A patient was successfully treated with corticosteroids, anti-CD20 and cyclophosphamide therapy.
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