Related Experiment Video
Updated: Dec 31, 2025
Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients
Published on: December 16, 2022
Association of postoperative covert stroke and cognitive dysfunction among elderly patients undergoing non-cardiac
Qianyu Cui1, Dexiang Wang1, Min Zeng1
1Anesthesiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Introduction:
The incidence of covert stroke and cognitive dysfunction has gradually increased due to an ageing population. Recently, a prospective cohort study reported perioperative covert stroke was associated with an increased risk of postoperative cognitive dysfunction (POCD) 1 year after non-cardiac surgery. However, the mechanism remains unclear.
Methods And Analysis:
This is a prospective observational trial aiming to investigate the cumulative incidence of perioperative covert stroke and test the hypothesis that perioperative covert stroke associates with POCD in elderly patients undergoing non-cardiac and non-neurological surgery. Data on risk factors, brain MRI, cognitive function evaluation and serum immune-inflammatory cytokines will be collected and analysed.
Ethics And Dissemination:
Ethical approval has been granted by the Medical Ethics Committee of Beijing Tiantan Hospital, Capital Medical University (reference number: KY2017-027-02). The results of this study will be disseminated through presentations at scientific conferences and publication in scientific journals.
Trial Registration Number:
NCT03081429.
