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Updated: Dec 31, 2025

Production of Extracellular Matrix Fibers via Sacrificial Hollow Fiber Membrane Cell Culture
Published on: February 2, 2019
Antimicrobial Properties of Extracellular Matrix Scaffolds for Tissue Engineering
Germán R Jiménez-Gastélum1,2, Elsa M Aguilar-Medina2, Eduardo Soto-Sainz3
1Faculty of Biology, Autonomous University of Sinaloa, Culiacan, Sinaloa 80010, Mexico.
Abstract:
The necessity to manufacture graft materials with superior biocompatibility capabilities and biodegradability characteristics for tissue regeneration has led to the production of extracellular matrix- (ECM-) based scaffolds. Among their advantages are better capacity to allow cell colonization, which enables its successful integration into the tissue surrounding the area to be repaired. In addition, it has been shown that some of these scaffolds have antimicrobial activity, preventing possible infections; therefore, it could be used as an alternative to control surgical infection and decrease the use of antimicrobial agents. The purpose of this review is to collect the existing information about antimicrobial activity of the ECM and their components.
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