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Updated: Dec 31, 2025

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

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Cardiac resynchronization therapy following Carillon® annuloplasty device for symptomatic heart failure and

Haqeel A Jamil1, Steven L Goldberg2,3, Klaus K Witte1

  • 1Division of Cardiovascular and Diabetes Research, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, LIGHT Building, Clarendon Way, Leeds LS2 9JT, UK.

European Heart Journal. Case Reports
|January 9, 2020
PubMed

Insights

This case study shows how combining transvenous mitral annuloplasty and cardiac resynchronization therapy can effectively manage patients with left ventricular systolic dysfunction, functional mitral regurgitation, and left bundle branch block.

Area of Science:

  • Cardiology
  • Medical Devices
  • Heart Failure Management

Background:

  • Left ventricular systolic dysfunction (LVSD) with functional mitral regurgitation (FMR) and left bundle branch block (LBBB) presents complex challenges.
  • Optimal medical therapy (OMT) may be insufficient for symptomatic patients with these co-existing conditions.
  • These comorbidities contribute to clinical deterioration and poorer prognosis.
Abstract

Keywords:
Cardiac resynchronization therapyCarillonCase reportFunctional mitral regurgitationHeart failureMitral annuloplasty

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