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Related Concept Videos

Vaccinations01:51

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Overview
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Development of Immunocompetence01:22

Development of Immunocompetence

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The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
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Teratogenicity01:07

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The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
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Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
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Mitral Valve Prolapse III: Nursing Management01:19

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The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...
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Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

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Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
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Updated: Dec 31, 2025

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Vaccination during pregnancy: current and possible future recommendations.

Kirsten Maertens1, Marjolein Rozemarie Paulien Orije2, Pierre Van Damme2

  • 1Centre for the Evaluation of Vaccination, Vaccine & Infectious Diseases Institute, University of Antwerp, Universiteitsplein 1, 2610, Wilrijk, Belgium. kirsten.maertens@uantwerp.be.

European Journal of Pediatrics
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PubMed
Summary

Maternal vaccination protects newborns by transferring antibodies. This review covers current and future recommendations for immunizing pregnant women against infectious diseases.

Keywords:
ImmunizationInfluenzaMaternalPertussisPregnancy

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Area of Science:

  • Immunology
  • Maternal and Child Health
  • Vaccinology

Background:

  • Maternal antibodies transferred during pregnancy and breastfeeding are crucial for neonatal protection against infections.
  • Pregnant women are increasingly targeted for vaccination during outbreaks and for diseases like influenza, pertussis, CMV, and GBS.

Purpose of the Study:

  • To review the rationale and mechanisms of maternal vaccination strategies.
  • To summarize current and future recommendations for maternal vaccination.

Main Methods:

  • Literature review of maternal vaccination strategies.
  • Analysis of current and emerging vaccine recommendations for pregnant women.

Main Results:

  • Maternal vaccination offers significant protection for both mothers and infants.
  • Tetanus, pertussis, and influenza vaccines are currently recommended during pregnancy in some regions.
  • New vaccines specifically for use during pregnancy are under development.

Conclusions:

  • Maternal vaccination is a key strategy for protecting neonates and mothers from infectious diseases.
  • The review provides an updated overview of maternal vaccination, including future prospects.