Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Spermatogenesis01:41

Spermatogenesis

120.8K
Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male...
120.8K
Infertility in Males01:23

Infertility in Males

489
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
489
Sperm Transport01:15

Sperm Transport

2.8K
The journey of sperm from its origin to the point of ejaculation begins within the seminiferous tubules of the testis. Here, Sertoli cells produce fluid that propels non-motile sperm through a series of conduits, starting with the straight tubules leading to the rete testis. This interconnected network of tubules acts as the initial pathway for sperm, guiding them into the efferent ductules and then into the epididymis for maturation.
The maturation phase occurs in the epididymis, where sperm...
2.8K
Testes: Histology01:27

Testes: Histology

2.6K
A tough, fibrous membrane, the tunica albuginea, covers the testes, extending inward to form fibrous partitions or septa, dividing them into internal compartments called lobules. Each lobule has 1 to 3 tightly coiled seminiferous tubules where sperm production occurs. These tubules merge into a tubular network at the back of the testis, known as the rete testis. It connects to 15 to 20 efferent ductules, leading to the epididymis.
The spermatogenic cells, responsible for producing sperm, are...
2.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

PSMA expression: enhancing prostate cancer diagnosis at the biopsy stage.

Minerva urology and nephrology·2026
Same author

Active surveillance for renal masses up to 2 cm: long-term oncological outcomes from a prospective multi-institutional study.

World journal of urology·2026
Same author

The impact of near-infrared photobiomodulation therapy on human oocyte rescue in vitro maturation.

Journal of photochemistry and photobiology. B, Biology·2026
Same author

Prognostic Value of Microvascular Resistance Reserve in Coronary Artery Disease: A Systematic Review and Meta-Analysis.

JACC. Cardiovascular interventions·2026
Same author

Enhancing Percutaneous Access: The «GENOA» Prone Modified Position.

Research and reports in urology·2026
Same author

Italian-translated EAU video for informed consent in PCNL: enhancing patient understanding and reducing anxiety: a prospective two-centre study.

World journal of urology·2026

Related Experiment Video

Updated: Dec 31, 2025

A Modified Vessel-Sparing Microsurgical Vasoepididymostomy
04:59

A Modified Vessel-Sparing Microsurgical Vasoepididymostomy

Published on: June 8, 2022

2.3K

Failure modes and effects analysis for testicular sperm extraction management process.

Pierandrea Canepa1, Caterina De Leo2, Ida Casciano1

  • 1S.S. Physiopathology of Human Reproduction, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.

Andrologia
|January 9, 2020
PubMed
Summary

Failure modes and effects analysis (FMEA) reduced risks in testicular sperm extraction (TESE) management. Implementing a standard operative procedure (SOP) significantly lowered high-risk steps and improved sample traceability.

Keywords:
FMEATESEclinical risk managementrisk assessment

More Related Videos

Vessel-Sparing Microsurgical Longitudinal Intussusception Vasoepididymostomy to Treat Epididymal Obstructive Azoospermia
06:28

Vessel-Sparing Microsurgical Longitudinal Intussusception Vasoepididymostomy to Treat Epididymal Obstructive Azoospermia

Published on: May 27, 2022

4.2K
Author Spotlight: Advanced Treatment of Seminal Duct Blockage Employing Endoscopy-Mediated Semen Channel Refluviation
03:51

Author Spotlight: Advanced Treatment of Seminal Duct Blockage Employing Endoscopy-Mediated Semen Channel Refluviation

Published on: December 8, 2023

4.2K

Related Experiment Videos

Last Updated: Dec 31, 2025

A Modified Vessel-Sparing Microsurgical Vasoepididymostomy
04:59

A Modified Vessel-Sparing Microsurgical Vasoepididymostomy

Published on: June 8, 2022

2.3K
Vessel-Sparing Microsurgical Longitudinal Intussusception Vasoepididymostomy to Treat Epididymal Obstructive Azoospermia
06:28

Vessel-Sparing Microsurgical Longitudinal Intussusception Vasoepididymostomy to Treat Epididymal Obstructive Azoospermia

Published on: May 27, 2022

4.2K
Author Spotlight: Advanced Treatment of Seminal Duct Blockage Employing Endoscopy-Mediated Semen Channel Refluviation
03:51

Author Spotlight: Advanced Treatment of Seminal Duct Blockage Employing Endoscopy-Mediated Semen Channel Refluviation

Published on: December 8, 2023

4.2K

Area of Science:

  • Reproductive Medicine
  • Quality Management Systems
  • Risk Assessment

Background:

  • Assisted reproduction technology centers perform testicular sperm extraction (TESE) for azoospermic patients.
  • Quality management programs require proactive risk evaluation to minimize procedural failures.
  • Failure Modes and Effects Analysis (FMEA) is a key tool for identifying and mitigating risks.

Purpose of the Study:

  • To assess risks associated with the TESE management process using FMEA.
  • To evaluate the effectiveness of corrective measures implemented via a standard operative procedure (SOP).

Main Methods:

  • A multidisciplinary team applied the FMEA method to the TESE management process.
  • Risk Priority Numbers (RPNs) were calculated for identified failure modes before and after SOP implementation.
  • The study involved identifying potential failure causes, effects, and risk levels.

Main Results:

  • The FMEA identified 19 potential failure modes across 4 process activities and 19 steps.
  • Implementation of the SOP led to a significant reduction in high/moderate risk phases (from 13 to 3).
  • Improvements in the traceability system eliminated 85% of low-occurrence risk steps.

Conclusions:

  • FMEA is an effective tool for multidisciplinary teams to enhance process understanding and identify critical steps.
  • Implementing corrective measures through SOPs improves compliance with traceability and conformity standards.
  • FMEA facilitates practical improvements in assisted reproduction technology procedures.