Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Generation of ciBMECs: Endothelial Cells Acquire Blood-Brain Barrier Identity and Function Through Wnt Activation.

Arteriosclerosis, thrombosis, and vascular biology·2026
Same author

The transcription factor EHF promotes the maturation and immunosuppression of conventional dendritic cells.

Nature communications·2026
Same author

Revisiting the blueprint for an interpretable virtual cell.

Nature reviews. Genetics·2026
Same author

Mouse lemur cell atlas informs primate genes, physiology and disease.

Nature·2025
Same author

A molecular cell atlas of mouse lemur, an emerging model primate.

Nature·2025
Same author

Characterizing resistant cellular states in nasopharyngeal carcinoma during EBV lytic induction.

Oncogene·2025
Same journal

Sodium-Based Battery Component Design: Imitating Lithium or Forging New Paths?

Small (Weinheim an der Bergstrasse, Germany)·2026
Same journal

Enhancing Birefringence of Sulphates by Polarity Modification in Planar Cations.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same journal

In Situ Atomic-Scale Observation of Preferential Premelting at Oxide Crystal Defects.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same journal

Thickness-Dependent Semiconductor-Metal Transition in Two-Dimensional Nonlayered Magnetic CuCo<sub>2</sub>S<sub>4</sub>.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same journal

Programmable Control Over Radical and Non‑Radical Pathways in Fenton‑Like Catalysis via Carbon‑Encapsulated Iron Nanoreactors.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same journal

Self-Powered MXene@Perovskite Thermoelectric Skin for Multimodal Mid-Infrared Sensing and Human Signal Recognition.

Small (Weinheim an der Bergstrasse, Germany)·2026
See all related articles

Related Experiment Video

Updated: Dec 31, 2025

Micropatterning and Assembly of 3D Microvessels
13:05

Micropatterning and Assembly of 3D Microvessels

Published on: September 9, 2016

12.3K

Recreating Physiological Environments In Vitro: Design Rules for Microfluidic-Based Vascularized Tissue Constructs.

Sin Yen Tan1, Ziuwin Leung2, Angela Ruohao Wu1,2

  • 1Department of Chemical and Biological Engineering, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong.

Small (Weinheim an Der Bergstrasse, Germany)
|January 9, 2020
PubMed
Summary
This summary is machine-generated.

Microfluidic technology offers a solution for engineering vascularized tissues in vitro by precisely controlling the microenvironment. This approach enhances the development of complex engineered tissues that mimic native physiological conditions.

Keywords:
biochemistrybiomechanicsin vitro modelsmicrofluidicstissue engineeringvasculatures

More Related Videos

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids
08:22

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids

Published on: August 11, 2017

16.3K
Author Spotlight: Creating Human Vascularized Micro-Tumors as Models for Translational Cancer Research
07:26

Author Spotlight: Creating Human Vascularized Micro-Tumors as Models for Translational Cancer Research

Published on: September 15, 2023

2.3K

Related Experiment Videos

Last Updated: Dec 31, 2025

Micropatterning and Assembly of 3D Microvessels
13:05

Micropatterning and Assembly of 3D Microvessels

Published on: September 9, 2016

12.3K
Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids
08:22

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids

Published on: August 11, 2017

16.3K
Author Spotlight: Creating Human Vascularized Micro-Tumors as Models for Translational Cancer Research
07:26

Author Spotlight: Creating Human Vascularized Micro-Tumors as Models for Translational Cancer Research

Published on: September 15, 2023

2.3K

Area of Science:

  • Biomedical Engineering
  • Tissue Engineering
  • Microfluidics

Background:

  • Vascularization is a critical challenge in creating functional engineered tissues that replicate native environments.
  • Current methods struggle to balance physiological complexity with operational simplicity.

Purpose of the Study:

  • To review design considerations for microfluidic-based in vitro models for vascularized engineered tissues.
  • To highlight microenvironment control strategies for advancing tissue engineering.

Main Methods:

  • Systematic review of microfluidic technologies for engineered tissue vascularization.
  • Analysis of design factors influencing microenvironment control.

Main Results:

  • Microfluidics enables precise control over biochemical and engineering cues within the vascular microenvironment.
  • Tunable parameters include coculture, matrix, growth factors, flow, and shear stress.

Conclusions:

  • Microfluidic platforms are essential for developing sophisticated vascularized engineered tissues.
  • Optimizing microenvironment control is key to future advancements in tissue engineering.