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Cerebral sinovenous thrombosis in a child with ulcerative colitis: A case report

Yue Liu1, Dongmei Ren2, Qiaoyu Zhou1

  • 1Department of Neurological Intensive Care Unit.

Medicine
|January 9, 2020
PubMed

Insights

Cerebral sinovenous thrombosis (CVT) in children with ulcerative colitis (UC) is rare but serious. Early diagnosis and anticoagulation therapy led to a full recovery, preventing fatal outcomes.

Area of Science:

  • Neurology
  • Gastroenterology
  • Pediatrics

Background:

  • Cerebral sinovenous thrombosis (CVT) is an infrequent but serious complication of inflammatory bowel disease (IBD).
  • CVT in IBD patients carries high risks of disability and mortality.

Observation:

  • A 12-year-old female with new-onset ulcerative colitis (UC) presented with acute hemiparesis and sensory loss.
  • Cerebral sinovenous thrombosis secondary to UC was diagnosed.

Findings:

  • The patient received blood transfusion, anticoagulation, digital subtraction angiography, and urokinase thrombolysis.
  • Complete functional recovery of limb movements was observed.
  • No recurrent stroke events occurred during a one-year follow-up.

Implications:

  • CVT can occur in pediatric patients with UC, highlighting the need for vigilance.
  • Prompt diagnosis and early anticoagulation are crucial for managing CVT in UC.
  • Timely intervention can prevent severe disability and mortality associated with this condition.
Abstract

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