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Updated: May 5, 2026

A Reversible, Non-invasive Method for Airway Resistance Measurements and Bronchoalveolar Lavage Fluid Sampling in Mice
Published on: April 14, 2010
Clinical investigation of fenoterol, a new bronchodilator, in asthma
Abstract:
In a randomized, double-blind, noncrossover, study, 28 asthmatic patients received either ephedrine or fenoterol (Th1165a) a new beta 2-sympathomimetic bronchodilator, for 90 days. Forced expiratory flows and volumes and plethysmography were performed after a single test dose on days 1, 45, and 90. The subjects' clinical course was followed for patient acceptance and side effects. Compared to ephedrine, Th1165a was demonstrated to be a potent bronchodilator with a prolonged duration of action. Adrenergic side effects were minimal, and no tolerance or toxicity was demonstrated.
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