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Updated: Dec 31, 2025

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
Published on: March 3, 2023
[Distribution and drug resistance analysis of secretion pathogens in 90 children with acute otitis media]
1Department of Otolaryngology,Putuo District People's Hospital,Zhoushan,316100,China.
Insights
Streptococcus pneumoniae is the primary cause of acute otitis media in children under three. Antibiotic resistance patterns vary significantly, highlighting the need for targeted treatment strategies.
Area of Science:
- Pediatrics
- Microbiology
- Infectious Diseases
Background:
- Acute otitis media (AOM) is a common childhood infection.
- Identifying causative pathogens and their antibiotic susceptibility is crucial for effective treatment.
Purpose of the Study:
- To determine the distribution of pathogenic bacteria in pediatric AOM.
- To analyze the antibiotic resistance patterns of these bacteria, particularly Streptococcus pneumoniae.
Main Methods:
- Retrospective analysis of clinical data from 90 pediatric AOM patients.
- Bacterial pathogen identification and antibiotic susceptibility testing.
- Age-based grouping ( <1, 1-3, >3 years) to compare pathogen prevalence.
Main Results:
- Pathogen detection rate was 75.6%, with Streptococcus pneumoniae being the most prevalent (61.8%).
- Streptococcus pneumoniae was significantly more common in children under 3 years old (Groups A and B) compared to older children (Group C).
- Variable resistance rates of Streptococcus pneumoniae to different antibacterial agents were observed.
Conclusions:
- Streptococcus pneumoniae is the predominant pathogen in pediatric AOM patients under 3 years of age.
- Antibiotic resistance varies among different antibacterial drugs, necessitating careful selection for treatment.
Abstract:
Objective:To analyze the pathogenic bacteria distribution and drug resistance of secretion in 90 child patients with acute otitis media. Method:The clinical data of 90 cases of acute otitis media child patients were retrospectively analyzed. The distribution of pathogenic bacteria in all child patients were analyzed. The child patients were divided into A group(less than 1 year old, n=38), B group (1 to 3 years old, n=27) and C group (more than 3 years old, n=25) according to the age. The streptococcus pneumoniae detection in each group and the streptococcus pneumoniae resistant to various antibacterial agents were compared. Result:The positive rate of pathogen detection in children was 75.6% (68/90), and the highest proportion was streptococcus pneumoniae with 61.8% (42/68). The detection rate of streptococcus pneumoniae in A and B group was significantly higher than that of C group (P<0.05). The resistance rate of streptococcus pneumoniae to different antibacterial drugs is quite different. Conclusion:Streptococcus pneumoniae is the main pathogenic bacterium in child patients with acute otitis media less than 3 years old, and different types of antibacterial drugs have different drug resistance.
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