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Related Concept Videos

Acute Pyelonephritis I: Introduction01:27

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Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
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Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
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The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
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Related Experiment Video

Updated: Dec 31, 2025

Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis
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Arcanobacterium pyogenes and encrusted pyelitis.

Albert Semaan1, Georges Abi Tayeh1, Josselin Abi Chebel1

  • 1Urology Department, Faculty of Medicine, Saint-Joseph University, Beirut, Lebanon.

Future Science OA
|January 10, 2020
PubMed
Summary
This summary is machine-generated.

Trueperella pyogenes, a bacterium typically affecting cattle, was identified as a cause of human urinary tract infections. This case highlights its potential role in encrusted pyelitis, particularly in recurrent infections.

Keywords:
Arcanobacterium pyogenesTrueperella pyogenesatypical pathogensencrusted pyelitishumanpyelitisrenal calcificationsurinary tract infections

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Area of Science:

  • Microbiology
  • Urology

Background:

  • Trueperella pyogenes is a known veterinary pathogen.
  • Human urinary tract infections (UTIs) are commonly caused by other bacteria.
  • T. pyogenes has not been previously reported as a cause of human UTIs.

Observation:

  • A 69-year-old male with a history of urological procedures presented with recurrent UTI symptoms.
  • Deep pelvic cultures during renoscopy revealed T. pyogenes.
  • The patient had undergone prior nephrolithotomy and ureteral reimplantation.

Findings:

  • T. pyogenes was successfully isolated from the patient's urinary tract.
  • Treatment with intravenous teicoplanin led to symptom resolution.
  • Imaging showed regression of bladder and ureteral thickening post-treatment.

Implications:

  • T. pyogenes can cause human urinary tract infections, including encrusted pyelitis.
  • This finding is significant in cases of persistent or recurring UTIs.
  • Further investigation into T. pyogenes as a human pathogen is warranted.