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Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis
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Arcanobacterium pyogenes and encrusted pyelitis

Albert Semaan1, Georges Abi Tayeh1, Josselin Abi Chebel1

  • 1Urology Department, Faculty of Medicine, Saint-Joseph University, Beirut, Lebanon.

Future Science OA
|January 10, 2020
PubMed
Abstract

Insights

Trueperella pyogenes, a bacterium typically affecting cattle, was identified as a cause of human urinary tract infections. This case highlights its potential role in encrusted pyelitis, particularly in recurrent infections.

Area of Science:

  • Microbiology
  • Urology

Background:

  • Trueperella pyogenes is a known veterinary pathogen.
  • Human urinary tract infections (UTIs) are commonly caused by other bacteria.
  • T. pyogenes has not been previously reported as a cause of human UTIs.

Observation:

  • A 69-year-old male with a history of urological procedures presented with recurrent UTI symptoms.
  • Deep pelvic cultures during renoscopy revealed T. pyogenes.
  • The patient had undergone prior nephrolithotomy and ureteral reimplantation.

Findings:

  • T. pyogenes was successfully isolated from the patient's urinary tract.
  • Treatment with intravenous teicoplanin led to symptom resolution.
  • Imaging showed regression of bladder and ureteral thickening post-treatment.

Implications:

  • T. pyogenes can cause human urinary tract infections, including encrusted pyelitis.
  • This finding is significant in cases of persistent or recurring UTIs.
  • Further investigation into T. pyogenes as a human pathogen is warranted.
Keywords:
Arcanobacterium pyogenesTrueperella pyogenesatypical pathogensencrusted pyelitishumanpyelitisrenal calcificationsurinary tract infections

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