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Assessing the Putative Anticryptococcal Properties of Crude and Clarified Extracts from Mollusks
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Pyrifenox, an ergosterol inhibitor, differentially affects Cryptococcus neoformans and Cryptococcus gattii

Vanessa K A Silva1, Robin C May2, Marcio L Rodrigues3,4

  • 1Programa de Pós-Graduação em Biologia Parasitária, Instituto Oswaldo Cruz (IOC), Fundação Oswaldo Cruz (FIOCRUZ), Rio de Janeiro, Brazil.

Medical Mycology
|January 10, 2020
PubMed
Summary

Pyrifenox inhibits fungal growth and capsule export in Cryptococcus, but is less effective against Cryptococcus gattii due to efflux pumps. This study explores pyrifenox as a potential antifungal agent.

Keywords:
Cryptococcusantifungalcapsuleglucuronoxylomannan

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