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Ocular manifestations in celiac disease: an overview
Fotios S Fousekis1, Andreas Katsanos2, Konstantinos H Katsanos1
1Department of Gastroenterology and Hepatology, School of Health Sciences, University Hospital of Ioannina, University of Ioannina, 45100, Ioannina, Greece.
Purpose:
To review and highlight the ocular manifestations associated with celiac disease (CD) and presentation of their pathogenetic mechanisms.
Methods:
A thorough review of the literature was performed using PubMed to identify articles about serrated polyposis syndrome. The search was performed using the search string: ("celiac disease" OR "coeliac disease") AND ("ocular manifestations" OR "eye" OR "orbitopathy" OR "uveitis" OR "neuro-ophthalmic manifestations"). Only articles in English were reviewed.
Results:
Several ocular symptoms and disorders have been associated with CD and are a result of defective intestinal absorption and immunological mechanisms. These include nyctalopia, dry eye, cataract, thyroid-associated orbitopathy, uveitis, central retinal vein occlusion and neuro-ophthalmic manifestations. In addition, CD-related ocular disease may represent the first manifestation of CD.
Conclusion:
CD may hold accountable for the development of ocular diseases of obscure etiology.
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