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Published on: July 27, 2018
Cutavirus: A newly discovered parvovirus on the rise
1Division of Clinical Microbiology, University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Abstract:
Cutavirus is a new member of the Parvoviridae family. It was first discovered in 2016 through unbiased metagenomics performed on fecal samples collected from patients with diarrhea, and also in skin biopsies collected from patients with cutaneous T-cell lymphoma (CTCL, also known as mycosis fungoides). We have systematically reviewed the literature to describe the discovery, genomic organization, prevalence, and geographic distribution of cutavirus.
Insights
Cutavirus, a novel Parvoviridae family member, was discovered in 2016. This review details its origins in human diarrhea and skin samples, and explores its global spread.
Area of Science:
- Virology
- Human Microbiome
- Dermatology
Background:
- Cutavirus is a recently identified virus belonging to the Parvoviridae family.
- Its initial discovery in 2016 stemmed from metagenomic analysis of diverse human samples.
Purpose of the Study:
- To systematically review and consolidate existing literature on cutavirus.
- To describe the discovery, genomic characteristics, prevalence, and geographical distribution of cutavirus.
Main Methods:
- Systematic literature review of scientific publications.
- Analysis of data from metagenomic studies on fecal and skin biopsy samples.
Main Results:
- Cutavirus was first detected in 2016 from patients with diarrhea and cutaneous T-cell lymphoma (CTCL).
- The review synthesizes information regarding its genomic organization, prevalence rates, and global distribution patterns.
Conclusions:
- Cutavirus represents a new viral entity with potential implications in human health.
- Further research is warranted to fully understand its pathogenic role and epidemiological significance.
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