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Gastrulation01:56

Gastrulation

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Gastrulation establishes the three primary tissues of an embryo: the ectoderm, mesoderm, and endoderm. This developmental process relies on a series of intricate cellular movements, which in humans transforms a flat, “bilaminar disc” composed of two cell sheets into a three-tiered structure. In the resulting embryo, the endoderm serves as the bottom layer, and stacked directly above it is the intermediate mesoderm, and then the uppermost ectoderm. Respectively, these tissue strata...
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Neurulation01:30

Neurulation

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Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the...
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Determining the Plane of Cell Division02:13

Determining the Plane of Cell Division

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Positioning the cell division plane is a critical step during development and cell differentiation, particularly during mitosis when the plane is essential for determining the size of the two daughter cells. The cell division plane is perpendicular to the plane of chromosome segregation, but different types of organisms have different cell division mechanisms to suit their morphology and function. 
Animal cells
In animal cells, the cleavage furrow forms along the plane of cell division...
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Cleavage and Blastulation01:33

Cleavage and Blastulation

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After a large-single-celled zygote is produced via fertilization, the process of cleavage occurs while zygotes travel through the uterine tube. Cleavage is a mitotic cell division that does not result in growth. With each round of successive cell division, daughter cells get increasingly smaller.
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Related Experiment Video

Updated: Dec 31, 2025

Dissection and Lateral Mounting of Zebrafish Embryos: Analysis of Spinal Cord Development
05:36

Dissection and Lateral Mounting of Zebrafish Embryos: Analysis of Spinal Cord Development

Published on: February 28, 2014

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Programmed cell death along the midline axis patterns ipsilaterality in gastrulation.

Lisandro Maya-Ramos1, Takashi Mikawa2

  • 1Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 94158, USA.

Science (New York, N.Y.)
|January 11, 2020
PubMed
Summary
This summary is machine-generated.

Bilateral symmetry is maintained by keeping cells on their own side. Extracellular matrix and programmed cell death at the embryonic midline prevent cells from crossing, ensuring ipsilateral development.

Failed At:

2026-06-19T13:28:30.861888+00:00

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