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Updated: Dec 31, 2025

Preterm EEG: A Multimodal Neurophysiological Protocol
Published on: February 18, 2012
Multimodal Neurologic Enhancement Improves Preterm Infants' Developmental Outcomes: A Longitudinal Pilot Study
Purpose:
The purpose of this study was to identify the long-term developmental effects of a NICU music therapy intervention, Multimodal Neurologic Enhancement, provided to preterm infants in the NICU.
Design:
Prospective randomized controlled study with one control group and one experimental group.
Sample:
Participants were medically stable preterm infants with a birth age of 31 and 6/7 weeks or less, admitted to a level-III NICU. A total of 84 participants were enrolled, and 48 completed the study.
Main Outcome Variable:
Post-discharge developmental scores on the Mullen Scales of Early Learning: AGS Edition.
Results:
The experimental group performed significantly better than the control group on the Visual Reception and Early Learning Composite scores.

