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Updated: Dec 31, 2025
Development of an Innovative LED-based Illumination Device for In Vitro Application of Photodynamic Therapy with Rose Bengal
Published on: September 12, 2025
[Research progress in endoscopic retrograde cholangiopancreatography-mediated photodynamic therapy for
Kunpeng Wang1, Li Xiong2, Zijian Zhang2
1Department of General Surgery, Second Xiangya Hospital, Central South University, Changsha 410011; Department of General Surgery, Taizhou Central Hospital (Affiliated Hospital of Taizhou College), Taizhou Zhejiang 318000, China.
Abstract:
The malignant degree of cholangiocarcinoma is high, and the early diagnosis is difficult. The vast majority of patients are unresectable when they are diagnosed. The patients have low quality of life and short survival cycle. Traditional radiotherapy and chemotherapy have poor efficacy and lead to side effects, and thus lack effective control measures for cholangiocarcinoma. Endoscopic retrograde cholangiopancreatography (ERCP) is an important method for diagnosing and treating biliary tract diseases. Photodynamic therapy (PDT) is a new local treatment for cholangiocarcinoma. In recent years, ERCP-mediated PDT treatment of cholangiocarcinoma has gradually emerged. ERCP-mediated PDT can effectively relieve the symptoms of patients with cholangiocarcinoma, improve the patients' quality of life, prolong the survival cycle, and is expected to become a new treatment for cholangiocarcinoma.
