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Maintaining health with renal disease or dysfunction.

L H Beck1

  • 1Program in Geriatric Medicine, University of Pennsylvania School of Medicine, Philadelphia.

Geriatrics
|December 1, 1988
PubMed
Summary

Kidney function naturally declines with age, impacting fluid balance. Chronic kidney insufficiency in older adults can worsen this decline, but proper management ensures patients remain functional.

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Area of Science:

  • Nephrology
  • Gerontology
  • Physiology

Background:

  • Aging is associated with natural anatomic and histologic changes in the kidney.
  • These age-related changes lead to a reduced capacity to manage fluid and solute imbalances.
  • Existing renal insufficiency can exacerbate age-related declines in kidney function.

Purpose of the Study:

  • To describe the age-related changes in renal function.
  • To explain how chronic renal insufficiency interacts with aging kidneys.
  • To emphasize the importance of management strategies for elderly patients with renal disease.

Main Methods:

  • Review of existing literature on renal physiology in aging.
  • Analysis of morphologic and histologic changes in the aging kidney.
  • Evaluation of the impact of superimposed chronic renal insufficiency.

Main Results:

  • Elderly individuals typically experience a decline in renal function, resembling mild chronic renal insufficiency.
  • Age-related kidney changes diminish the ability to respond to physiological stresses.
  • Chronic renal insufficiency accelerates age-related renal functional decline.

Conclusions:

  • Age-related renal changes are a normal physiological process.
  • The combination of aging and chronic renal insufficiency presents unique challenges.
  • Effective management allows most elderly patients with renal disease to maintain a high level of function.

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