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Updated: Dec 31, 2025

Control of Eating Behavior Using a Novel Feedback System
Published on: May 8, 2018
Neural Control and Modulation of Thirst, Sodium Appetite, and Hunger
Vineet Augustine1, Sangjun Lee2, Yuki Oka2
1Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California, USA; Department of Neuroscience, The Scripps Research Institute, La Jolla, California, USA.
Abstract:
The function of central appetite neurons is instructing animals to ingest specific nutrient factors that the body needs. Emerging evidence suggests that individual appetite circuits for major nutrients-water, sodium, and food-operate on unique driving and quenching mechanisms. This review focuses on two aspects of appetite regulation. First, we describe the temporal relationship between appetite neuron activity and consumption behaviors. Second, we summarize ingestion-related satiation signals that differentially quench individual appetite circuits. We further discuss how distinct appetite and satiation systems for each factor may contribute to nutrient homeostasis from the functional and evolutional perspectives.
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