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Corneal Donor Tissue Preparation for Descemet's Membrane Endothelial Keratoplasty

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Descemet membrane detachment.

Deepali Singhal¹, Pranita Sahay¹, Siddhi Goel¹

¹Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Survey of Ophthalmology

|January 11, 2020

Summary

This summary is machine-generated.

Descemet membrane detachment (DMD) after eye surgery can threaten vision. Prompt diagnosis and management, often surgical for severe cases, typically lead to good visual outcomes.

Keywords:

Descemet membrane Descemet membrane detachment anterior segment optical coherence tomography descemetopexy perfluoropropane

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Area of Science:

Ophthalmology
Corneal Surgery

Background:

Descemet membrane detachment (DMD) is a vision-threatening complication, most common after cataract surgery but also seen after other ocular procedures.
Risk factors include advanced age, endothelial diseases, hard cataracts, long surgical times, and surgical trauma.

Purpose of the Study:

To review the classification, diagnosis, and management of Descemet membrane detachment (DMD).

Main Methods:

Review of literature on Descemet membrane detachment (DMD).
Classification of DMD based on configuration, height, extent, length, and pupil position.
Use of anterior segment optical coherence tomography (AS-OCT) for diagnosis and management planning.

Main Results:

Most DMDs are peripheral and resolve spontaneously with conservative management.
Large, central DMDs with scrolled edges or length >2 mm often require surgical intervention.
Descemetopexy is the gold standard surgical treatment, with other options including mechanical tamponade and keratoplasty.

Conclusions:

Prompt diagnosis and timely management of DMD are crucial for favorable visual outcomes.
Surgical intervention is necessary for significant or non-resolving DMD cases.