Related Experiment Video
Updated: Dec 31, 2025
Left Lung Orthotopic Transplantation in a Juvenile Porcine Model for ESLP
Published on: February 14, 2022
Novel Antiplatelet Perioperative Bridging Protocol for Lung Lobectomy: A Case Report
Sora Ely1,2, Dana A Dominguez1,2, Jeffrey B Velotta3
1Department of Surgery, University of California San Francisco-East Bay, Oakland.
Introduction:
Some patients with cardiac stents will need thoracic surgery during the dual antiplatelet therapy (DAPT) period. When surgery cannot be safely delayed to allow 1 year of uninterrupted DAPT, appropriate perioperative management of anticoagulation is critical.
Case Presentation:
A patient treated with new drug-eluting stents and DAPT was concomitantly diagnosed with lung cancer and required a lobectomy. We describe the novel addition of ticagrelor (a short-acting oral antiplatelet agent) to eptifibatide (a short-acting intravenous antiplatelet agent) to bridge DAPT for surgery.
Discussion:
This ticagrelor-eptifibatide perioperative bridge resulted in decreased preoperative hospitalization compared with eptifibatide alone. There were no associated perioperative cardiac or bleeding complications.
