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Screening for bacteriuria with Clinitec-200.

H M Doran1, J G Kensit

  • 1Department of Microbiology, Greenwich District Hospital, London.

Journal of Clinical Pathology
|October 1, 1988
PubMed
Summary
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Evaluating a reagent strip test for bacteriuria (bacteria in urine) showed it could reduce workload by 40%. However, it yielded a 10% false negative rate, making it uneconomical and unacceptable.

Area of Science:

  • Clinical Microbiology
  • Diagnostic Testing
  • Urinalysis

Background:

  • Bacteriuria diagnosis traditionally involves urine culture.
  • Rapid screening methods are sought to reduce laboratory workload and costs.

Purpose of the Study:

  • To evaluate the diagnostic accuracy and economic viability of a multi-reagent strip test for detecting bacteriuria.

Main Methods:

  • A total of 669 urine specimens were tested using multiple reagent strips (blood, nitrite, leucocyte esterase).
  • Results were compared against a standard diagnostic method (implied, not stated).

Main Results:

  • The reagent strip test identified 267 negative specimens, potentially reducing culture workload by 40%.
  • However, 13 false-negative results occurred, representing 10% of all confirmed bacteriuria cases.

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  • The screening test required additional time, negating manpower savings and slightly increasing overall costs.
  • Conclusions:

    • The evaluated reagent strip test for bacteriuria is not economically viable.
    • The test produces an unacceptable rate of false-negative results, potentially delaying diagnosis and treatment.