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Updated: Dec 31, 2025

Lesion Explorer: A Video-guided, Standardized Protocol for Accurate and Reliable MRI-derived Volumetrics in Alzheimer's Disease and Normal Elderly
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An improved algorithm of white matter hyperintensity detection in elderly adults.

T Ding1, A D Cohen1, E E O'Connor2

  • 1University of Pittsburgh, Pittsburgh.

Neuroimage. Clinical
|January 14, 2020
PubMed
Summary

We developed OASIS-AD, a novel method for automatically segmenting white matter hyperintensities in older adults. This approach improves accuracy in detecting these brain changes, crucial for understanding aging and Alzheimer's disease.

Keywords:
Alzheimer's diseaseBrainMRIOASISStatistical methods neuroimagingWMH segmentation

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