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Updated: Dec 31, 2025

Identification and Protection of the Recurrent Laryngeal Nerve during Transoral Robotic Thyroidectomy
Published on: October 24, 2025
Risk factors predisposing for recurrent laryngeal nerve palsy following thyroid malignancy surgery: experience from a
Supreet Singh Nayyar1, Shivakumar Thiagarajan2, Akshat Malik1
1Department of Head and Neck Surgical Oncology, Homi Bhabha National Institute, Tata Memorial Hospital, Parel, Mumbai, 400012, India.
Background:
Postoperative recurrent laryngeal nerve (RLN) palsy is one of the major morbidities encountered after thyroid surgery. The risk further increases when surgery is performed for thyroid malignancies.
Methodology:
A retrospective study of patients who underwent hemi, total or completion thyroidectomy at our institute between June 2017 to May 2019 were analyzed. We assessed factors that predisposed to the development of RLN palsy.
Results:
The study comprised of 228 patients. A total of 400 nerves were at risk. The RLN palsy rate was 6.8% (n = 27). On univariate and multivariate analysis, the risk of RLN palsy was seen most with pT4a tumor (OR = 8.5), gross extra-thyroidal extension (ETE) (OR = 3.5) and tracheo-esophageal groove (TEG) (OR = 2.8) involvement, followed by aggressive histopathology, and central compartment node positivity.
Conclusion:
pT4a tumors, gross ETE, and TEG involvement were the leading causes predisposing for the development of RLN palsy in our series.
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