Granular Cell Tumor: A Rare Breast Lesion

Area of Science:

• Oncology
• Pathology

Background:

• Granular cell tumors (GCTs) are uncommon neoplasms originating from Schwann cells.
• While GCTs can occur anywhere, breast involvement is rare, accounting for a small percentage of all cases.

Observation:

• A 54-year-old woman presented with a breast lesion suspicious for malignancy on ultrasound, mammography, and MRI.
• Core needle biopsy confirmed the lesion as a granular cell tumor.

Findings:

• Histopathological examination of the surgical specimen post-lumpectomy confirmed the diagnosis of granular cell tumor.
• The tumor mimicked malignant breast lesions on various imaging modalities.

Implications:

• This case underscores the importance of considering GCTs in the differential diagnosis of breast lesions, especially when imaging findings are suspicious.
• Accurate diagnosis is crucial to avoid misclassification as breast carcinoma and ensure appropriate patient management.