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Pregnancy in myositis and scleroderma.
Sirajum Munira1, Lisa Christopher-Stine2
1Saint Agnes Hospital Internal Medicine Residency Program, Ascension Health, Postal Address: 10003, Autumn view lane, Ellicott city, Baltimore, MD-21042, USA.
Best Practice & Research. Clinical Obstetrics & Gynaecology
|January 14, 2020
Summary
Pregnancy outcomes for myositis and scleroderma patients are often favorable with careful management. Active maternal autoimmune disease during pregnancy, however, is linked to adverse outcomes, necessitating personalized care.
Area of Science:
- Rheumatology
- Autoimmune Diseases
- Reproductive Medicine
Background:
- Myositis and scleroderma are rare autoimmune conditions predominantly affecting women of reproductive age.
- Concurrent disease and pregnancy are infrequent due to the rarity of these conditions.
- Autoimmune disease activity can increase during pregnancy.
Purpose of the Study:
- To provide an overview of pregnancy outcomes in patients with myositis and scleroderma.
- To highlight the impact of maternal disease activity on pregnancy.
- To emphasize the need for individualized management strategies.
Main Methods:
- Literature review of pregnancy outcomes in myositis and scleroderma.
- Analysis of factors influencing maternal and fetal health.
- Synthesis of current management approaches.
Main Results:
- Favorable pregnancy outcomes are achievable with diligent management.
- Active maternal myositis or scleroderma during pregnancy correlates with adverse outcomes.
- Personalized management plans are crucial for optimizing results.
Conclusions:
- Careful management can lead to positive pregnancy outcomes in myositis and scleroderma.
- Controlling maternal disease activity is key to preventing adverse pregnancy events.
- Tailored treatment based on disease status and comorbidities is essential.
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