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Correction: A fast-dissolving microneedle array loaded with chitosan nanoparticles to evoke systemic immune responses
Zhilin Li1, Yingju He, Li Deng
1Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China. denglisunny@163.com.
Journal of Materials Chemistry. B
|January 14, 2020
Summary
A correction is issued for a study on fast-dissolving microneedle arrays. The original research explored chitosan nanoparticles for systemic immune responses in mice.
Area of Science:
- Biomaterials Science
- Immunology
- Nanotechnology
Context:
- The original study investigated the potential of advanced drug delivery systems for vaccine development.
- Microneedle technology offers a minimally invasive approach for transdermal delivery.
- Chitosan nanoparticles are explored for their biocompatibility and immune-adjuvant properties.
Purpose:
- To correct inaccuracies in the original publication regarding experimental procedures and data interpretation.
- To ensure the scientific record accurately reflects the findings on microneedle-based immune stimulation.
- To provide clarity on the efficacy of chitosan nanoparticle-loaded microneedles in eliciting systemic immune responses.
Summary:
- This correction addresses errors in the original article concerning the formulation and characterization of chitosan nanoparticles.
- Clarifications are provided on the methodology used for loading nanoparticles onto the microneedle array.
- The revised details ensure accurate reporting of the observed immune responses in the mouse model.
Impact:
- Ensures the integrity and reliability of scientific data in the field of biomaterials and immunology.
- Facilitates accurate future research building upon the corrected findings.
- Reinforces the importance of rigorous verification in the development of novel drug delivery systems.

