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Updated: Dec 31, 2025

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Developing a roadmap to determine per- and polyfluoroalkyl substances-microbial population interactions.

Denis M O'Carroll1, Thomas C Jeffries2, Matthew J Lee1

  • 1School of Civil and Environmental Engineering, Water Research Centre, University of New South Wales, Sydney, NSW 2052, Australia.

The Science of the Total Environment
|January 14, 2020
PubMed
Summary

Per- and polyfluoroalkyl substances (PFAS) impact microbial communities in groundwater, with some bacteria showing positive correlations and others negative. These findings offer insights into PFAS biodegradation and ecosystem effects.

Keywords:
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Area of Science:

  • Environmental Science
  • Microbiology
  • Environmental Chemistry

Background:

  • Per- and polyfluoroalkyl substances (PFAS) are persistent environmental contaminants.
  • Legacy firefighting training areas are significant sources of PFAS contamination.
  • Understanding PFAS interactions with microbial communities is crucial for remediation.

Purpose of the Study:

  • To assess the relationship between PFAS and microbial communities in groundwater.
  • To investigate PFAS transport and degradation.
  • To identify microbial genera associated with varying PFAS concentrations.

Main Methods:

  • Collected over 40 groundwater samples from a PFAS-impacted site.
  • Analyzed PFAS chemistry and microbial community structure.
  • Correlated PFAS concentrations with microbial genus abundance.

Main Results:

  • Differential transport of PFAS based on chain-length and head group observed.
  • Evidence of PFAS degradation, specifically 6:2 fluorotelomer sulfonate (6:2 FTS).
  • Over 100 microbial genera showed significant associations with PFAS chemistry, with varying positive and negative correlations.

Conclusions:

  • PFAS constituents are not the primary drivers of microbial community structure but show significant associations.
  • Specific genera like Oxalobacteraceae and Desulfococcus correlate strongly with PFAS presence.
  • Findings suggest potential for PFAS biodegradation technologies and highlight ecosystem health impacts.