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Related Concept Videos

Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

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Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
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Heart Failure VI: Adjunct Therapies01:22

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Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
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Implantation of the Syncardia Total Artificial Heart
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Permanent Implantable Cardiac Support Systems.

Jan F Gummert1, Axel Haverich, Jan D Schmitto

  • 1Clinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Centre, North Rhine Westphalia, Bad Oeynhausen, Germany; Department of Cardiovascular Surgery, Charité, Universitätsmedizin Berlin; German Center of Cardiovascular Research (Deutsches Zentrum für Herz-Kreislauf-Forschung) - DZHK, Partner Site Berlin; Department of Cardiac, Thoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany; Department of Thoracic and Cardiovascular Surgery, German Heart Center, Berlin, Germany.

Deutsches Arzteblatt International
|January 15, 2020
PubMed
Summary
This summary is machine-generated.

Permanent ventricular assist devices (VADs) significantly improve survival and mobility for severe heart failure patients. While complications exist, VADs offer a vital alternative to heart transplantation.

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Area of Science:

  • Cardiology
  • Medical Devices
  • Heart Failure Management

Background:

  • Ventricular assist devices (VADs) are crucial for managing severe congestive heart failure.
  • Nearly 1000 VADs are implanted annually in Germany for advanced heart failure.
  • VADs are miniaturized pumps providing continuous blood flow, powered externally.

Purpose of the Study:

  • To review indications, therapeutic effects, and complications of permanent VADs.
  • To assess the role of VADs as alternatives or bridges to cardiac transplantation.

Main Methods:

  • Selective literature review.
  • Inclusion of guidelines and registry data.
  • Discussion of clinical outcomes and adverse events.

Main Results:

  • One-year survival rates range from 69% to 81%, significantly exceeding conservative treatment.
  • Patients experience improved mobility (129-220m longer walking distance) and quality of life (28-37 points higher EQ-5D scores) at six months.
  • Potential severe complications include infection, right-heart failure, hemorrhage, pump thrombosis, stroke, and death.

Conclusions:

  • VAD implantation offers a life-extending option for severe heart failure patients.
  • VADs serve as a bridge to transplantation or a destination therapy when transplant is not feasible.
  • Careful patient selection and management are crucial to mitigate complications.