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Published on: June 10, 2025
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Short-term mortality in end-stage heart failure patients
Jose Maria Verdú-Rotellar1, Esther Calero2, Rosa Abellana3
1Gerencia Atención Primaria de Barcelona, Institut Català de la Salut, Barcelona, Spain; Primary Health Care University Research Institute Jordi Gol (IDIAPJGol), Barcelona, Spain; School of Medicine, Universitat Autonoma de Barcelona, Bellaterra, Spain.
Atencion Primaria
|January 15, 2020
Summary
Factors like male gender, older age, and low BMI increase short-term mortality in advanced heart failure (HF). Low blood pressure, poor kidney function, cancer, and high diuretic doses predict long-term mortality in HF patients.
Area of Science:
- Cardiology
- Geriatrics
- Public Health
Background:
- Advanced heart failure (HF) presents significant challenges in patient management and prognosis.
- Identifying key mortality predictors is crucial for optimizing care in end-stage HF patients.
Purpose of the Study:
- To analyze the primary factors influencing short-term and long-term mortality in patients with advanced heart failure (HF).
- To identify easily measurable variables that can aid in clinical decision-making for advanced HF stages.
Main Methods:
- A multicenter cohort study involving 1148 patients with advanced HF (NYHA IV).
- Patients were followed for one year, with mortality assessed at 1, 3, 6, and 12 months using multivariate logistic regression.
Main Results:
- Male gender, advanced age, and decreased body mass index (BMI < 20kg/m²) were associated with higher short-term mortality.
- Low systolic blood pressure, reduced glomerular filtration, malignancy, and higher loop diuretic doses correlated with increased medium- and long-term mortality.
- Low BMI was a significant risk factor across the entire follow-up period.
Conclusions:
- Short-term mortality in advanced HF is significantly influenced by demographic factors and BMI.
- Long-term survival is impacted by comorbidities like reduced kidney function and malignancy, alongside treatment intensity.
- These findings provide valuable, measurable indicators to guide clinical strategies for patients in the most advanced stages of heart failure.
Keywords:
End of lifeEpidemiologyEpidemiologíaFactores pronósticosFin de vidaHeart failureInsuficiencia cardíacaPrognostic factorsMore Related Videos
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