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Plasma self-sufficiency in Spain.

Ll Puig Rovira1

  • 1Blood and Tissue Bank (Banc de Sang I Teixits, BST), Barcelona, Spain.

Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis
|January 15, 2020
PubMed
Summary

Spain faces challenges in plasma self-sufficiency, with decreasing whole blood donations impacting immunoglobulin and albumin supplies despite increased plasmapheresis. Measures are needed to address this critical healthcare supply issue.

Keywords:
HemoderivativesPlasmaPlasmapheresisTransfusion

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Area of Science:

  • Biomedical Sciences
  • Public Health
  • Healthcare Management

Background:

  • Spain's current plasma-derived medicinal product self-sufficiency relies on whole blood units and plasmapheresis programs.
  • Current supply levels are 42.9% for intravenous immunoglobulin (IVIG) and 68.4% for albumin.
  • Decreasing whole blood donations and rising IVIG consumption are creating a supply deficit.

Purpose of the Study:

  • To analyze the current state of plasma self-sufficiency in Spain.
  • To identify the factors contributing to the shortfall in plasma-derived products.
  • To propose necessary measures for improving the plasma supply chain.

Main Methods:

  • Analysis of national data on whole blood donations.
  • Review of plasmapheresis program yields.
  • Assessment of intravenous immunoglobulin and albumin consumption trends.
  • Evaluation of Spain's current plasma self-sufficiency metrics.

Main Results:

  • Despite an increase in plasmapheresis procedures, the decline in whole blood donations has not been offset.
  • The gap between plasma supply and demand for IVIG and albumin is widening.
  • Spain's self-sufficiency in these critical plasma products remains suboptimal.

Conclusions:

  • Urgent interventions are required to bolster plasma collection in Spain.
  • Strategies must address both increasing donations and managing product demand.
  • Ensuring a stable supply of plasma-derived medicinal products is crucial for public health.