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Updated: Dec 31, 2025

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Published on: December 23, 2022
First Occurrence of the OXA-198 Carbapenemase in Enterobacterales
Rémy A Bonnin1,2, Agnès B Jousset3,2, Lauraine Gauthier3,2
1EA7361, Université Paris-Sud, Université Paris-Saclay, LabEx Lermit, Bacteriology-Hygiene Unit, APHP, Hôpital Bicêtre, EERA "Evolution and Ecology of Resistance to Antibiotics" Unit, Institut Pasteur-APHP-Université Paris Sud, Le Kremlin-Bicêtre, France remy.bonnin@u-psud.fr.
Abstract:
A carbapenem-resistant Citrobacter sp. was recovered from routine screening of multidrug-resistant bacteria. This isolate coproduced OXA-48 and OXA-198. OXA-48 was carried by the prototypical IncL plasmid, whereas OXA-198 was carried by a peculiar IncHI-type plasmid. This carbapenemase gene was inserted within a class 1 integron located on a conjugative plasmid. This report describes the first occurrence of OXA-198 in Enterobacterales.
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