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Updated: Dec 31, 2025

Real-time Breath Analysis by Using Secondary Nanoelectrospray Ionization Coupled to High Resolution Mass Spectrometry
Published on: March 9, 2018
Non-invasive and Time-dependent Blood-sugar Monitoring via Breath-derived CO2 Correlation Using Gas Chromatograph
Cheng-Huang Lin1, Luo-Xian Wu2, Kuan-Hao Chen2
1Department of Chemistry, National Taiwan Normal University, Tingchow Rd., Taipei, 10617, Taiwan. chenglin@ntnu.edu.tw.
Abstract:
A clear and positive correlation between the CO2 concentration and the blood-sugar level has been observed via a non-invasive and time-dependent monitoring of CO2 concentration from human breath, which is carried out by using a home-made gas chromatography (GC)/milli-whistle compact analyzer. The time-dependent sampling of the CO2 concentration correlated between 5.0 to 5.6% (1% = 104 ppm) in accordance with blood-sugar level variations of 80 to 110 mg/dL. The analytical method results in a rapid, continuous and non-invasive determination of blood-sugar level via measurement of the CO2 concentration exhaled from the lungs.

