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Related Experiment Video

Updated: Dec 31, 2025

Three-Dimensional Reconstruction of Orbital Fractures

Three-Dimensional Reconstruction of Orbital Fractures

Published on: May 16, 2025

Multifocal Thrombophlebitis and Orbital Cellulitis.

Alojzija Hočevar^1,2, Daša Šuput Skvarča¹, Matija Tomšič^1,2

¹Department of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia.

The American Journal of Case Reports

|January 15, 2020

Summary

Multifocal superficial thrombophlebitis is a rare condition. Two cases suggest a potential new systemic inflammatory disease involving orbital inflammation, distinct from known causes.

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Area of Science:

Internal Medicine
Ophthalmology
Rheumatology

Background:

Multifocal superficial thrombophlebitis is a rare condition with a broad differential diagnosis.
Identifying the underlying cause is crucial for patient management.
Orbital inflammation can be associated with various systemic conditions.

Observation:

Two patients presented with systemic inflammatory response, multifocal superficial thrombophlebitis, and orbital inflammation.
No defined background disease was identified in either case.
The clinical presentation was consistent but idiopathic.

Findings:

The combination of multifocal superficial thrombophlebitis and orbital inflammation may indicate a distinct systemic illness.
The absence of a clear underlying etiology in these cases is notable.
This pattern suggests a potentially new medical condition.

Implications:

This presentation may represent a previously unrecognized systemic medical condition.
Further research is needed to define this condition and its characteristics.
Recognition of this pattern could aid in earlier diagnosis and management of similar cases.