Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL): An Open Wound

Since 2017, there have been an increasing number of reported cases regarding breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) in the literature. Although significant attention was dispensed for this relevant issue, there is no consensus on what the trigger points for disease development are. BIA-ALCL trigger point speculation includes textured breast implants, bacterial contamination, and genetic factors. However, little attention is given by the literature regarding gel bleeding and the toxicity of polydimethylsiloxane. This opinion-based article aims to report our experience in a prospective study of breast implants and share our knowledge regarding silicone-induced granuloma of breast implant capsule. LEVEL OF EVIDENCE V: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.