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Clinicopathologic and treatment features of aggressive angiomyxoma: a case report
Chen Lin1, Fei Huang2, Fen Li3
1Department of Pathology, Basic Medical Sciences, Xinjiang Medical University No. 393 Xinyi Road, Urumqi 830011, China.
Objective:
The present study is to accumulate clinicopathologic and treatment data on aggressive angiomyxoma (AA), a rare tumor.
Methods:
Various clinical findings were analyzed in 9 patients with AA at Affiliated Tumor Hospital of Xinjiang Medical University from 1996 to 2016.
Results:
Nine patients (8 females and 1 male) were included in the present study, with an age range from 14 to 63 years (median age, 33.4 years). The sites of tumor in 6 cases were perineum and vagina, right breast, left pelvic peritoneum and right groin (male). Gross examination showed that the tumor was solid and soft, with unclear boundary but no capsule. The cut surface was gray and jelly-like. According to microscopic examination, the tumor had invasive growth, and small fusiform or star-shaped cells being dispersed in a myxoid background, enclosing several capillary structures with a thin wall. The initial treatment was localized excision. Follow-up showed that 2 patients died from cardiovascular and cerebrovascular disease, 2 patients had local recurrence, 2 patients were withdrawn, and others had neither local recurrence nor distant metastasis. Follow-up time was 3-25 years.
Conclusion:
AA is a rare tumor that occurs predominantly in females. Local resection is appropriate to manipulate the tumor, and local recurrence is common.
