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Prosthetic Joint Infection of a Revision Knee Arthroplasty with Candida parapsilosis

Martine Christine Keuning1, Aziz Al Moujahid2, Wierd Pieter Zijlstra1

  • 1Department of Orthopaedic Surgery, Medical Center Leeuwarden, Leeuwarden, Netherlands.

Case Reports in Orthopedics
|January 15, 2020
PubMed

Insights

A rare knee replacement infection caused by Candida parapsilosis was successfully treated. The patient received a two-stage exchange arthroplasty combined with local and systemic antifungal therapies.

Area of Science:

  • Infectious Diseases
  • Orthopedic Surgery
  • Mycology

Background:

  • Total knee arthroplasty (TKA) is a common orthopedic procedure.
  • Periprosthetic joint infections (PJIs) are a serious complication following TKA.
  • Candida species, particularly Candida parapsilosis, are increasingly recognized as causes of PJIs.

Observation:

  • A case of a TKA infected with Candida parapsilosis is presented.
  • The patient presented with symptoms indicative of a deep joint infection.

Findings:

  • Successful treatment was achieved using a multi-modal approach.
  • The treatment regimen included a two-stage exchange arthroplasty.
  • Local and systemic antifungal administration was integral to the treatment protocol.

Implications:

  • This case highlights the successful management of a challenging PJI caused by Candida parapsilosis.
  • The combination of surgical intervention and targeted antifungal therapy offers a viable strategy.
  • Further research into optimal treatment protocols for fungal PJIs is warranted.

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